Glutathione prevents chronic oscillating glucose intake induced cell dedifferentiation and failure Cell Death & Disease Glutathione is such an important antioxidant in human physiology, meaning it acts to combat oxidative stress. Strategies for increasing glutathione include: Consume sulfur rich foods like cruciferous vegetables Ensure you get Alpha hydroxybutyrate and Prediabetes: Thinking beyond glucose and HgbA1c Frontiers Hexokinase linked glycolytic overload and unscheduled glycolysis in hyperglycemia induced pathogenesis of insulin resistance, beta cell glucotoxicity, and diabetic vascular complications Paul Thornalley