Ôoku: The Inner Chambers, Vol. 3oku: The Inner Chambers, Vol. 3 by Eisner nominated Fumi Yoshinaga presents an alternative history of Edo era Japan where the men are dying out, and women have taken up the reins of power, including the shoguns seat. In Edo period Japan, a strange new disease called the Redface Pox has begun to prey on the country's men. Within eighty years of the first outbreak, the male population has fallen by seventy five percent. Women have taken on all the roles