Curcumin 500 with BioperineCurcumin is the active component in turmeric. This curcumin 500 with Bioperine supplement comes with a black pepper extract that has the potential to increase curcumin's bioavailability, promoting absorption. Curcumin has a long history of use. Its support extends to the liver, colon, musculoskeletal and cellular functions, as well as performing antioxidant defense and helping the body's natural detoxification system.