Melanosis Ilei Clinical Gastroenterology and Hepatology Constipation, Disorders of Defecation, and Anal Pain Abdominal Key What the Color and Consistency of Your Poop Says About Your Health MELANOSIS COLI** Melanosis coli is a disorder of pigmentation of the bowel wall. Histology demonstrates pigment laden macrophages It is associated with laxative abuse, especially **anthraquinone compounds such as senna**