Health effects and known pathology associated with the use of E cigarettes ScienceDirect Chronic Obstructive Pulmonary Disease (COPD). Some diagnoses become so common that we stop questioning them. An elderly smoker with breathlessness? COPD. A wheezy patient in the emergency? COPD exacerbation. But bedside medicine Association of electronic cigarette use and risk of COPD: a systematic review and meta analysis npj Primary Care Respiratory Medicine The evidence is clear: Young E cigarette users suffer from respiratory symptoms American Lung Association